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Byung-Chul Lee 1 Article
A Case of Painful Hemimasticatory Spasm with Masseter Muscle Hypertrophy Responsive to Botulinum Toxin
Jin-Hyuck Kim, Seok-Won Han, Yun Joong Kim, Jooyong Kim, Mi-Suh Oh, Hyeo-Il Ma, Byung-Chul Lee
J Mov Disord. 2009;2(2):95-97.
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AbstractAbstract PDF

Hemimasticatory spasm (HMS) is a rare disorder of the trigeminal nerve characterized by paroxysmal involuntary contractions of the unilateral jaw-closing muscles. HMS has been frequently described in association with facial hemiatrophy or localized scleroderma. A 42-year-old female presented with involuntary paroxysmal spasms of the left face, of 6 months duration. Her lower face on the left was markedly hypertrophied without skin lesions. An electrophysiological study indicated that the masseter reflexes and masseteric silent period were attenuated on the affected side. Surface electromyography demonstrated irregular bursts of motor unit potentials at high frequencies up to 200 Hz. Magnetic resonance imaging of the head showed marked hypertrophy of the left masseter muscle. Biopsy of the hypertrophied masseter muscle was normal. Repeated local injections of botulinum toxin noticeably reduced the size of the hypertrophied muscle as well as improved the patient’s symptoms.


Citations to this article as recorded by  
  • Hemimasticatory spasm: a series of 17 cases and a comprehensive review of the literature
    Kazuya Yoshida
    Frontiers in Neurology.2024;[Epub]     CrossRef
  • Hemimasticatory spasm: possibilities of treatment with injections of botulinum neuroprotein type A (case report)
    L. U. Valieva, A. S. Pankratov, O. R. Orlova
    Neurology, Neuropsychiatry, Psychosomatics.2022; 14(3): 62.     CrossRef
  • Bilateral Hemimasticatory spasm in a patient with hypereosinophilic syndrome
    Kyung Ah Woo, Han-Joon Kim, Hyeyoung Park, Beomseok Jeon
    Parkinsonism & Related Disorders.2021; 93: 55.     CrossRef
  • Hemimasticatory spasm. Own experience of using botulinum neuroprotein type A
    A. N. Korenko, A. V. Amelin, A. A. Timofeeva
    The Scientific Notes of the Pavlov University.2021; 28(3): 47.     CrossRef
  • Parry-Romberg Syndrome With Hemimasticatory Spasm: A Rare Combination
    Guang-can Chen, Min-jie Chen, Wen-bin Wei, Yun-bo Hao
    Journal of Craniofacial Surgery.2020; 31(2): e205.     CrossRef
  • Hemi Masticatory Spasm: Series of 7 Cases and Review of Literature
    Divya M. Radhakrishnan, Vinay Goyal, Garima Shukla, Mamta Bhushan Singh, M. Ramam
    Movement Disorders Clinical Practice.2019; 6(4): 316.     CrossRef

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