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Hye-Young Sung 2 Articles
Gastrointestinal Autonomic Dysfunction in Patients with Parkinson’s Disease
Joong-Seok Kim, Hye-Young Sung
J Mov Disord. 2015;8(2):76-82.   Published online May 31, 2015
DOI: https://doi.org/10.14802/jmd.15008
  • 41,706 View
  • 268 Download
  • 43 Web of Science
  • 45 Crossref
AbstractAbstract PDF
Currently, gastrointestinal dysfunctions in Parkinson’s disease (PD) are well-recognized problems and are known to be an initial symptom in the pathological process that eventually results in PD. Gastrointestinal symptoms may result from the involvement of either the central or enteric nervous systems, or these symptoms may be side effects of antiparkinsonian medications. Weight loss, excessive salivation, dysphagia, nausea/gastroparesis, constipation, and defecation dysfunction all may occur. Increased identification and early detection of these symptoms can result in a significant improvement in the quality of life for PD patients.

Citations

Citations to this article as recorded by  
  • Regulation of Pain Perception by Microbiota in Parkinson Disease
    Zulmary Manjarres, Margarita Calvo, Rodrigo Pacheco, Habibeh Khoshbouei
    Pharmacological Reviews.2024; 76(1): 7.     CrossRef
  • Emerging wearable technologies for multisystem monitoring and treatment of Parkinson’s disease: a narrative review
    Yasmine M. Kehnemouyi, Todd P. Coleman, Peter A. Tass
    Frontiers in Network Physiology.2024;[Epub]     CrossRef
  • ICAM-1 may promote the loss of dopaminergic neurons by regulating inflammation in MPTP-induced Parkinson’s disease mouse models
    Fen Zhang, Lixin Pan, Changlin Lian, Zhifeng Xu, Hongda Chen, Wenjie Lai, Xiaojue Liang, Qiyuan Liu, Haomin Wu, Yukai Wang, Pande Zhang, Guohua Zhang, Zhen Liu
    Brain Research Bulletin.2024; 214: 110989.     CrossRef
  • N-acetyl-L-leucine protects MPTP-treated Parkinson’s disease mouse models by suppressing Desulfobacterota via the gut-brain axis
    Zhifeng Xu, Changlin Lian, Lixin Pan, Wenjie Lai, Fen Zhang, Lingmei Peng, Sijie Zhou, Guanghua Zhao, Xuezhu Yang, Guohua Zhang, Zefeng Tan, Yukai Wang
    Brain Research Bulletin.2023; 202: 110729.     CrossRef
  • Anesthetic Considerations for Cataract Surgery in Patients with Parkinson’s Disease: A Narrative Review
    Alyssa Chiew, David Mathew, Chandra M. Kumar, Edwin Seet, Farnad Imani, Seyed-Hossein Khademi
    Anesthesiology and Pain Medicine.2023;[Epub]     CrossRef
  • Gut-Brain Axis and Neurological Disorders-How Microbiomes Affect our Mental Health
    Nirav Yogesh Bhatia, Manjiri Prabhakar Jalgaonkar, Anuja Balu Hargude, Atul P. Sherje, Manisha Jignesh Oza, Gaurav Mahesh Doshi
    CNS & Neurological Disorders - Drug Targets.2023; 22(7): 1008.     CrossRef
  • A look back at the prodromal findings in Parkinson’s disease
    Seyed-Amirabbas Ahadiat, Zeinab Hosseinian
    Bulletin of the National Research Centre.2023;[Epub]     CrossRef
  • Parkinson’s disease and gut microbiota: from clinical to mechanistic and therapeutic studies
    Xuxiang Zhang, Beisha Tang, Jifeng Guo
    Translational Neurodegeneration.2023;[Epub]     CrossRef
  • Association between malnutrition and motor/non-motor symptoms in elderly with Parkinson disease
    Heewon Bae, Sang-Won Ha
    Journal of Geriatric Neurology.2023; 2(2): 58.     CrossRef
  • Gastrointestinal Sensory Neuropathy and Dysmotility in Fabry Disease: Presentations and Effect on Patient's Quality of Life
    Nir Bar, Amel Karaa, Katheryn Kiser, Braden Kuo, Claire Zar-Kessler
    Clinical and Translational Gastroenterology.2023; 14(12): e00633.     CrossRef
  • Nutritional aspects in Parkinson’s disease
    Paulina Gątarek, Joanna Kałużna-Czaplińska
    Critical Reviews in Food Science and Nutrition.2022; 62(23): 6467.     CrossRef
  • Are We What We Eat? Impact of Diet on the Gut–Brain Axis in Parkinson’s Disease
    Margherita Alfonsetti, Vanessa Castelli, Michele d’Angelo
    Nutrients.2022; 14(2): 380.     CrossRef
  • Factors Contributing to Malnutrition in Parkinson's Disease Patients With Freezing of Gait
    Li-Li Zhang, Liang Zhang, Jingde Dong, Ying Zhao, Xiao-Ping Wang
    Frontiers in Neurology.2022;[Epub]     CrossRef
  • Gut microbiota and inflammation in Parkinson’s disease: Pathogenetic and therapeutic insights
    Tong Guo, Li Chen
    European Journal of Inflammation.2022; 20: 1721727X2210837.     CrossRef
  • Exploring the multifactorial aspects of Gut Microbiome in Parkinson’s Disease
    Sujith Pavan, Arvind N. Prabhu, Sankar Prasad Gorthi, Bhabatosh Das, Ankur Mutreja, Vignesh Shetty, Thandavarayan Ramamurthy, Mamatha Ballal
    Folia Microbiologica.2022; 67(5): 693.     CrossRef
  • Psychobiotics: the Influence of Gut Microbiota on the Gut-Brain Axis in Neurological Disorders
    Parvin Oroojzadeh, Saber Yari Bostanabad, Hajie Lotfi
    Journal of Molecular Neuroscience.2022; 72(9): 1952.     CrossRef
  • Cardiac sympathetic denervation could be associated with dysphagia in Parkinson's disease
    Jinyoung Youn, George Umemoto, Eungseok Oh, Jinse Park, Wooyoung Jang, Yoon-Sang Oh, Hee-Tae Kim, Jin Whan Cho, Shinsuke Fujioka, Yoshio Tsuboi
    Frontiers in Neurology.2022;[Epub]     CrossRef
  • The interplay between the gut-brain axis and the microbiome: A perspective on psychiatric and neurodegenerative disorders
    Yasir Bashir, Asad U. Khan
    Frontiers in Neuroscience.2022;[Epub]     CrossRef
  • Human gut microbiota and its association with pathogenesis and treatments of neurodegenerative diseases
    Zhong Chen, Javeria Maqbool, Faiqa Sajid, Ghulam Hussain, Tao Sun
    Microbial Pathogenesis.2021; 150: 104675.     CrossRef
  • Novel compound FLZ alleviates rotenone-induced PD mouse model by suppressing TLR4/MyD88/NF-κB pathway through microbiota–gut–brain axis
    Zhe Zhao, Fangyuan Li, Jingwen Ning, Ran Peng, Junmei Shang, Hui Liu, Meiyu Shang, Xiu-Qi Bao, Dan Zhang
    Acta Pharmaceutica Sinica B.2021;[Epub]     CrossRef
  • Murine Esophagus Expresses Glial-Derived Central Nervous System Antigens
    Christopher Kapitza, Rittika Chunder, Anja Scheller, Katherine S. Given, Wendy B. Macklin, Michael Enders, Stefanie Kuerten, Winfried L. Neuhuber, Jürgen Wörl
    International Journal of Molecular Sciences.2021; 22(6): 3233.     CrossRef
  • Fecal Microbiota Transplantation Exerts a Protective Role in MPTP-Induced Parkinson’s Disease via the TLR4/PI3K/AKT/NF-κB Pathway Stimulated by α-Synuclein
    Zhe Zhong, Weijie Chen, Huan Gao, Ningning Che, Min Xu, Lanqing Yang, Yingfang Zhang, Min Ye
    Neurochemical Research.2021; 46(11): 3050.     CrossRef
  • ATH434 Reverses Colorectal Dysfunction in the A53T Mouse Model of Parkinson’s Disease
    Shanti Diwakarla, Rachel M. McQuade, Remy Constable, Olivia Artaiz, Enie Lei, Kevin J. Barnham, Paul A. Adlard, Robert A. Cherny, Madeleine R. Di Natale, Hongyi Wu, Xin-yi Chai, Victoria A. Lawson, David I. Finkelstein, John B. Furness
    Journal of Parkinson's Disease.2021; 11(4): 1821.     CrossRef
  • The role of microbiota-gut-brain axis in neuropsychiatric and neurological disorders
    Katarzyna Socała, Urszula Doboszewska, Aleksandra Szopa, Anna Serefko, Marcin Włodarczyk, Anna Zielińska, Ewa Poleszak, Jakub Fichna, Piotr Wlaź
    Pharmacological Research.2021; 172: 105840.     CrossRef
  • Transplantation of gut microbiota derived from Alzheimer’s disease mouse model impairs memory function and neurogenesis in C57BL/6 mice
    Namkwon Kim, Seung Ho Jeon, In Gyoung Ju, Min Sung Gee, Jimin Do, Myung Sook Oh, Jong Kil Lee
    Brain, Behavior, and Immunity.2021; 98: 357.     CrossRef
  • Exploring the Role of Orexinergic Neurons in Parkinson’s Disease
    Sachin Kumar, Tapan Behl, Aayush Sehgal, Sukhbir Singh, Neelam Sharma, Saurabh Bhatia, Ahmed Al-Harassi, Mohammed M. Abdel-Daim, Simona Bungau
    Neurotoxicity Research.2021; 39(6): 2141.     CrossRef
  • Fecal microbiota transplantation protects rotenone-induced Parkinson’s disease mice via suppressing inflammation mediated by the lipopolysaccharide-TLR4 signaling pathway through the microbiota-gut-brain axis
    Zhe Zhao, Jingwen Ning, Xiu-qi Bao, Meiyu Shang, Jingwei Ma, Gen Li, Dan Zhang
    Microbiome.2021;[Epub]     CrossRef
  • Chronic isolation stress is associated with increased colonic and motor symptoms in the A53T mouse model of Parkinson’s disease
    Shanti Diwakarla, David I. Finkelstein, Remy Constable, Olivia Artaiz, Madeleine Di Natale, Rachel M. McQuade, Enie Lei, Xin‐yi Chai, Mitchell T. Ringuet, Linda J. Fothergill, Victoria A. Lawson, Laura J. Ellett, Joel P. Berger, John B. Furness
    Neurogastroenterology & Motility.2020;[Epub]     CrossRef
  • Impact of gastrointestinal physiology on drug absorption in special populations––An UNGAP review
    Cordula Stillhart, Katarina Vučićević, Patrick Augustijns, Abdul W. Basit, Hannah Batchelor, Talia R. Flanagan, Ina Gesquiere, Rick Greupink, Daniel Keszthelyi, Mikko Koskinen, Christine M. Madla, Christophe Matthys, Goran Miljuš, Miriam G. Mooij, Neil Pa
    European Journal of Pharmaceutical Sciences.2020; 147: 105280.     CrossRef
  • Estado nutricional de idosos com doença de Parkinson e seus fatores associados: uma revisão integrativa
    Nívola Beatriz Mendonça de Arruda, Suelane Renata de Andrade Silva, Nadja Maria Jorge Asano, Maria das Graças Wanderley de Sales Coriolano
    Revista Brasileira de Geriatria e Gerontologia.2020;[Epub]     CrossRef
  • Probiotics for Parkinson’s Disease
    Gazerani
    International Journal of Molecular Sciences.2019; 20(17): 4121.     CrossRef
  • Hyper-serotonergic state determines onset and progression of idiopathic Parkinson’s disease
    Eliseu da Cruz Moreira-Junior
    Medical Hypotheses.2019; 133: 109399.     CrossRef
  • Constipation Increases Disability and Decreases Dopamine Levels in the Nigrostriatal System through Gastric Inflammatory Factors in Parkinson’s Disease
    Yongtao Zhou, Yusheng Su, Weihua Xu, Wei Wang, Shukun Yao
    Current Neurovascular Research.2019; 16(3): 241.     CrossRef
  • α-Synuclein Regulates Development and Function of Cholinergic Enteric Neurons in the Mouse Colon
    M. Swaminathan, C. Fung, D.I. Finkelstein, J.C. Bornstein, J.P.P. Foong
    Neuroscience.2019; 423: 76.     CrossRef
  • Neuroprotective effects of fecal microbiota transplantation on MPTP-induced Parkinson’s disease mice: Gut microbiota, glial reaction and TLR4/TNF-α signaling pathway
    Meng-Fei Sun, Ying-Li Zhu, Zhi-Lan Zhou, Xue-Bing Jia, Yi-Da Xu, Qin Yang, Chun Cui, Yan-Qin Shen
    Brain, Behavior, and Immunity.2018; 70: 48.     CrossRef
  • Dysbiosis of gut microbiota and microbial metabolites in Parkinson’s Disease
    Meng-Fei Sun, Yan-Qin Shen
    Ageing Research Reviews.2018; 45: 53.     CrossRef
  • Increased risk of all‐cause mortality associated with domperidone use in Parkinson's patients: a population‐based cohort study in the UK
    Marina Simeonova, Frank de Vries, Sander Pouwels, Johanna H. M. Driessen, Hubert G.M. Leufkens, Suzanne M. Cadarette, Andrea M. Burden
    British Journal of Clinical Pharmacology.2018; 84(11): 2551.     CrossRef
  • Clostridium butyricum MIYAIRI 588 as Adjunctive Therapy for Treatment-Resistant Major Depressive Disorder: A Prospective Open-Label Trial
    Tsuyoshi Miyaoka, Misako Kanayama, Rei Wake, Sadayuki Hashioka, Maiko Hayashida, Michiharu Nagahama, Shihoh Okazaki, Satoko Yamashita, Shoko Miura, Hiroyuki Miki, Hiroyuki Matsuda, Masahiro Koike, Muneto Izuhara, Tomoko Araki, Keiko Tsuchie, Ilhamuddin Ab
    Clinical Neuropharmacology.2018; 41(5): 151.     CrossRef
  • Role of Microbiota in Neurodegenerative Diseases
    C. V. Sobol
    Russian Journal of Developmental Biology.2018; 49(6): 297.     CrossRef
  • α-Synuclein in the colon and premotor markers of Parkinson disease in neurologically normal subjects
    Joong-Seok Kim, In-Seok Park, Hyung-Eun Park, Su-Young Kim, Jung A Yun, Chan Kwon Jung, Hye-Young Sung, Jin-Kwon Lee, Won-Kyung Kang
    Neurological Sciences.2017; 38(1): 171.     CrossRef
  • Validation of the Korean Version of the Scale for Outcomes in Parkinson’s Disease-Autonomic
    Ji-Young Kim, In-Uk Song, Seong-Beom Koh, Tae-Beom Ahn, Sang Jin Kim, Sang-Myung Cheon, Jin Whan Cho, Yun Joong Kim, Hyeo-Il Ma, Mee-Young Park, Jong Sam Baik, Phil Hyu Lee, Sun Ju Chung, Jong-Min Kim, Han-Joon Kim, Young-Hee Sung, Do Young Kwon, Jae-Hyeo
    Journal of Movement Disorders.2017; 10(1): 29.     CrossRef
  • Switching from an oral dopamine receptor agonist to rotigotine transdermal patch: a review of clinical data with a focus on patient perspective
    Sun Ju Chung, Mahnaz Asgharnejad, Lars Bauer, Arturo Benitez, Babak Boroojerdi, Tanja Heidbrede, Allison Little, Han Joon Kim
    Expert Review of Neurotherapeutics.2017; 17(7): 737.     CrossRef
  • Clostridium butyricum attenuates cerebral ischemia/reperfusion injury in diabetic mice via modulation of gut microbiota
    Jing Sun, Fangyan Wang, Zongxin Ling, Xichong Yu, Wenqian Chen, Haixiao Li, Jiangtao Jin, Mengqi Pang, Huiqing Zhang, Junjie Yu, Jiaming Liu
    Brain Research.2016; 1642: 180.     CrossRef
  • Cancer incidence among Parkinson's disease patients in a 10-yrs time-window around disease onset: A large-scale cohort study
    Chava Peretz, Ron Gurel, Violet Rozani, Tanya Gurevich, Baruch El-Ad, Judith Tsamir, Nir Giladi
    Parkinsonism & Related Disorders.2016;[Epub]     CrossRef
  • An Incidental Finding of a Radiopaque Pill following Cervical Spinal Surgery in a Parkinson's Disease Patient
    Bon Sub Gu, Soo-Jung Choi, Byoungwoo Yoo, Koon Hee Han, Jong Kyu Park, Young-Seok Lee, Jin Hoon Park
    Korean Journal of Spine.2015; 12(3): 153.     CrossRef
The Frequency and Severity of Gastrointestinal Symptoms in Patients with Early Parkinson’s Disease
Hye-Young Sung, Jeong-Wook Park, Joong-Seok Kim
J Mov Disord. 2014;7(1):7-12.   Published online April 30, 2014
DOI: https://doi.org/10.14802/jmd.14002
  • 18,714 View
  • 189 Download
  • 60 Web of Science
  • 61 Crossref
AbstractAbstract PDF
Objective: Although gastrointestinal dysfunctions occur in the majority of patients with Parkinson’s disease (PD), they are often unrecognized because many patients remain relatively asymptomatic in the early stage. We investigated the frequency of gastrointestinal symptoms in patients with PD using newly developed gastrointestinal symptom questionnaires.
Methods: Early PD patients with a symptom duration not exceeding 3 years were included in this study. All PD patients were evaluated using a questionnaire, which consisted of three relevant domains: oropharyngoesophageal (10 items); gastric (3 items); and intestinal-anorectal (7 items). The frequency of symptoms was calculated as a proportion with an item score ≥ 2.
Results: Of the 54 patients enrolled, 48 patients (88.9%) responded that bowel symptoms developed before the onset of Parkinsonian motor symptoms, and four patients reported that the onset of two types of symptoms (i.e., bowel and neurological) occurred approximately simultaneously, with only months between them. The frequencies of gastrointestinal symptoms are as follows: speech disturbance (40.7%), drooling (24.1%), sense of getting stuck (31.5%), choking (27.8%), globus pharyngis (16.7%), repetitive deglutition (29.6%), pain during swallowing (5.6%), food regurgitation (3.7%), acid reflux (7.4%), nausea/ vomiting (11.1%), early satiety (16.7%), postprandial fullness (14.8%), epigastric soreness (9.3%), abdominal pain (3.7%), constipation (46.3%), excessive strain during defecation (33.3%), fecal incontinence (7.4%), tenesmus (20.4%), loose stool or diarrhea (3.7%), and difficulty in relaxing anal sphincter (11.1%). Two patients were scored at zero.
Conclusions: Our findings confirm that gastrointestinal dysfunction occurs in early PD in relatively high frequency.

Citations

Citations to this article as recorded by  
  • Neuroimmune Connectomes in the Gut and Their Implications in Parkinson’s Disease
    Beatriz Thomasi, Luisa Valdetaro, Brian Gulbransen, Ana Lúcia Tavares-Gomes
    Molecular Neurobiology.2024; 61(4): 2081.     CrossRef
  • Effect of Lycium ruthenicum and Lycium barbarum intake on Parkinson based on microbiology and metabonomics: A randomized pilot trial
    Lingyu Wu, Liwen Chu, Hongdou Cao, Qi Tian, Hua Gao, Jinghong Huo, Qinghan Gao
    Food Bioscience.2024; 57: 103548.     CrossRef
  • The missing piece of the puzzle – The key role of the dietitian in the management of Parkinson's disease
    Richelle Flanagan, Carley Rusch, Fiona E. Lithander, Indu Subramanian
    Parkinsonism & Related Disorders.2024; 121: 106021.     CrossRef
  • Gastric-filling ultrasonography to evaluate gastric motility in patients with Parkinson's disease
    Xianwei Zou, Xiaqing Chen, Yanxia Wen, Xiaofeng Jing, Man Luo, Fengyue Xin, Yao Tang, Mengfei Hu, Jian Liu, Fan Xu
    Frontiers in Neurology.2024;[Epub]     CrossRef
  • Persistent intolerable abdominal pain in patients with Parkinson’s disease
    Hiroshi Kataoka, Kazuma Sugie
    Clinical Neurology and Neurosurgery.2023; 224: 107558.     CrossRef
  • Striatal Dopaminergic Loss and Dysphagia in Parkinson Disease
    Ji Hwan Kim, Jonghu Jeon, Young Lee, Seung Min Kim, Miju Cheon, Jun Yup Kim
    Clinical Nuclear Medicine.2023; 48(2): 143.     CrossRef
  • The gut microbiota is an emerging target for improving brain health during ageing
    Marcus Boehme, Katherine Elizabeth Guzzetta, Caroline Wasén, Laura Michelle Cox
    Gut Microbiome.2023;[Epub]     CrossRef
  • 6-OHDA-Induced Changes in Colonic Segment Contractility in the Rat Model of Parkinson’s Disease
    Maria Del Pilar Murillo, Ebba Johansson, Victoria Bryntesson, Patrik Aronsson, Gunnar Tobin, Michael Winder, Thomas Carlsson, Stephen Fink
    Gastroenterology Research and Practice.2023; 2023: 1.     CrossRef
  • Efficacy of acupuncture for the treatment of Parkinson’s disease-related constipation (PDC): A randomized controlled trial
    Ying-Jia Li, Ian-I Leong, Jing-Qi Fan, Ming-Yue Yan, Xin Liu, Wei-Jing Lu, Yuan-Yuan Chen, Wei-Qiang Tan, Yu-Ting Wang, Li-Xing Zhuang
    Frontiers in Neuroscience.2023;[Epub]     CrossRef
  • Considerations for developing a targeted amino acid supplement for people with Parkinson’s disease that promotes health while accounting for pathophysiology and medication interference
    Jacob E Earp, Cristina Colon-Semenza, Dara L LoBuono
    Nutrition Reviews.2023; 81(8): 1063.     CrossRef
  • Lactobacillus plantarum CCFM405 against Rotenone-Induced Parkinson’s Disease Mice via Regulating Gut Microbiota and Branched-Chain Amino Acids Biosynthesis
    Chuanqi Chu, Leilei Yu, Yiwen Li, Hang Guo, Qixiao Zhai, Wei Chen, Fengwei Tian
    Nutrients.2023; 15(7): 1737.     CrossRef
  • The longitudinal progression of autonomic dysfunction in Parkinson's disease: A 7-year study
    Charlotte B. Stewart, David Ledingham, Victoria K. Foster, Kirstie N. Anderson, Sahana Sathyanarayana, Debra Galley, Nicola Pavese, Jacopo Pasquini
    Frontiers in Neurology.2023;[Epub]     CrossRef
  • Association of dysphagia with altered brain glucose metabolism in Parkinson's disease
    Ji Yeon Oh, Eui Jin An, Young Lee, Seung Min Kim, Miju Cheon, Jun Yup Kim
    CNS Neuroscience & Therapeutics.2023; 29(9): 2498.     CrossRef
  • Differential Findings on Anorectal Manometry in Patients with Parkinson's Disease and Defecatory Dysfunction
    Wendy Zhou, George Triadafilopoulos, Brooke Gurland, Houssam Halawi, Laren Becker, Patricia Garcia, Linda Nguyen, Mitchell Miglis, Srikanth Muppidi, Dong‐In Sinn, Safwan Jaradeh, Leila Neshatian
    Movement Disorders Clinical Practice.2023; 10(7): 1074.     CrossRef
  • Abdominal pain in Parkinson’s disease
    A.A. Pilipovich, O.V. Vorobyova, S.A. Makarov
    Russian Journal of Pain.2023; 21(2): 12.     CrossRef
  • Microbiome-Based Therapies in Parkinson’s Disease: Can Tuning the Microbiota Become a Viable Therapeutic Strategy?
    Adejoke Y. Onaolapo, Folusho O. Ojo, Anthony T. Olofinnade, Joshua Falade, Ismail A. Lawal, Olakunle J. Onaolapo
    CNS & Neurological Disorders - Drug Targets.2023; 22(9): 1355.     CrossRef
  • Constipation in Parkinson's Disease
    Eamonn M. M. Quigley
    Seminars in Neurology.2023; 43(04): 562.     CrossRef
  • Autonomic symptoms in early-stage Parkinson’s patients and their relationship with cognition and disease parameters
    Esma KOBAK TUR, Eren GÖZKE
    Anatolian Current Medical Journal.2023; 5(4): 498.     CrossRef
  • Lower gastrointestinal dysfunction in patients with Parkinson’s disease
    A.A. Pilipovich, O.V. Vorob’eva, S.A. Makarov, A.V. Kuchuk
    Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova.2023; 123(12): 42.     CrossRef
  • Related Effects of Methamphetamine on the Intestinal Barrier via Cytokines, and Potential Mechanisms by Which Methamphetamine May Occur on the Brain-Gut Axis
    Yuansen Li, Deshenyue Kong, Ke Bi, Huayou Luo
    Frontiers in Medicine.2022;[Epub]     CrossRef
  • Alpha-synuclein and tau are abundantly expressed in the ENS of the human appendix and monkey cecum
    Alexandra D. Zinnen, Jonathan Vichich, Jeanette M. Metzger, Julia C. Gambardella, Viktoriya Bondarenko, Heather A. Simmons, Marina E. Emborg, Stephan N. Witt
    PLOS ONE.2022; 17(6): e0269190.     CrossRef
  • Management of dysphagia and gastroparesis in Parkinson’s disease in real-world clinical practice – Balancing pharmacological and non-pharmacological approaches
    Roongroj Bhidayasiri, Warongporn Phuenpathom, Ai Huey Tan, Valentina Leta, Saisamorn Phumphid, K. Ray Chaudhuri, Pramod Kumar Pal
    Frontiers in Aging Neuroscience.2022;[Epub]     CrossRef
  • Mechanisms of development of constipation in Parkinson’s disease and therapeutic approaches
    E.A. Katunina, N.N. Shipilova, D.A. Katunin
    Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova.2022; 122(8): 21.     CrossRef
  • Intestinal Permeability, Dysbiosis, Inflammation and Enteric Glia Cells: The Intestinal Etiology of Parkinson’s Disease
    Huijia Yang, Song Li, Weidong Le
    Aging and disease.2022; 13(5): 1381.     CrossRef
  • The interplay between the gut-brain axis and the microbiome: A perspective on psychiatric and neurodegenerative disorders
    Yasir Bashir, Asad U. Khan
    Frontiers in Neuroscience.2022;[Epub]     CrossRef
  • Clinical features and relative factors of constipation in a cohort of Chinese patients with Parkinson's disease
    Bai-Hua Sun, Tao Wang, Nian-Ying Li, Qiong Wu, Jin Qiao
    World Journal of Gastrointestinal Pharmacology and Therapeutics.2021; 12(1): 21.     CrossRef
  • Characterization of Gastrointestinal Symptom Type and Severity in Parkinson's Disease: A Case–Control Study in an Australian Cohort
    Jade E. Kenna, Megan C. Bakeberg, Anastazja M. Gorecki, Alfred Chin Yen Tay, Samantha Winter, Frank L. Mastaglia, Ryan S. Anderton
    Movement Disorders Clinical Practice.2021; 8(2): 245.     CrossRef
  • Granisetron, a selective 5-HT3 antagonist, reduces L-3,4-dihydroxyphenylalanine-induced abnormal involuntary movements in the 6-hydroxydopamine-lesioned rat
    Cynthia Kwan, Imane Frouni, Dominique Bédard, Adjia Hamadjida, Philippe Huot
    Behavioural Pharmacology.2021; 32(1): 43.     CrossRef
  • Deglutition Impairment during Dual Task in Parkinson Disease Is Associated with Cognitive Status
    Luciana Grolli Ardenghi, Alana Verza Signorini, Gerson Schulz Maahs, Fabio Selaimen, Konrado Massing Deutsch, Silvia Dornelles, Carlos Roberto de Mello Rieder
    International Archives of Otorhinolaryngology.2021; 25(01): e41.     CrossRef
  • Spectrum of Non-Motor Symptoms in Parkinson's Disease
    Maithrayie Kumaresan, Safeera Khan
    Cureus.2021;[Epub]     CrossRef
  • Onset of Skin, Gut, and Genitourinary Prodromal Parkinson's Disease: A Study of 1.5 Million Veterans
    Gregory D. Scott, Miranda M. Lim, Matthew G. Drake, Randy Woltjer, Joseph F. Quinn
    Movement Disorders.2021; 36(9): 2094.     CrossRef
  • The Gastrointestinal Dysfunction Scale for Parkinson's Disease
    Marta Camacho, Julia C. Greenland, Caroline H. Williams‐Gray
    Movement Disorders.2021; 36(10): 2358.     CrossRef
  • The role of microbiota-gut-brain axis in neuropsychiatric and neurological disorders
    Katarzyna Socała, Urszula Doboszewska, Aleksandra Szopa, Anna Serefko, Marcin Włodarczyk, Anna Zielińska, Ewa Poleszak, Jakub Fichna, Piotr Wlaź
    Pharmacological Research.2021; 172: 105840.     CrossRef
  • Neuro-Immunity and Gut Dysbiosis Drive Parkinson’s Disease-Induced Pain
    Katiane Roversi, Natalia Callai-Silva, Karine Roversi, May Griffith, Christos Boutopoulos, Rui Daniel Prediger, Sébastien Talbot
    Frontiers in Immunology.2021;[Epub]     CrossRef
  • Autonomic dysfunction in Parkinson’s disease: Implications for pathophysiology, diagnosis, and treatment
    Zhichun Chen, Guanglu Li, Jun Liu
    Neurobiology of Disease.2020; 134: 104700.     CrossRef
  • Double‐Blind, Randomized, Placebo‐Controlled Trial of DA‐9701 in Parkinson's Disease: PASS‐GI Study
    Ji‐Hyun Choi, Jee‐Young Lee, Jin Whan Cho, Seong‐Beom Koh, Young Soon Yang, Dalla Yoo, Cheol‐Min Shin, Hee Tae Kim
    Movement Disorders.2020; 35(11): 1966.     CrossRef
  • Parkinson disease and the gut: new insights into pathogenesis and clinical relevance
    R. Alberto Travagli, Kirsteen N. Browning, Michael Camilleri
    Nature Reviews Gastroenterology & Hepatology.2020; 17(11): 673.     CrossRef
  • Expanding the brain researcher's toolkit
    Viviana Gradinaru
    Science.2020; 369(6504): 637.     CrossRef
  • Excessive buccal saliva in patients with Parkinson’s disease of the French COPARK cohort
    Olivier Rascol, Laurence Negre-Pages, Philippe Damier, Arnaud Delval, Pascal Derkinderen, Alain Destée, Margherita Fabbri, Wassilios G. Meissner, Amine Rachdi, François Tison, Santiago Perez-Lloret
    Journal of Neural Transmission.2020; 127(12): 1607.     CrossRef
  • Struktur und Efferenzen der Substantia nigra pars compacta beim idiopathischen Parkinson-Syndrom
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    PLOS ONE.2018; 13(1): e0190078.     CrossRef
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    Neurobiology of Disease.2018; 112: 106.     CrossRef
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    Current Treatment Options in Gastroenterology.2018; 16(4): 489.     CrossRef
  • Transdermal rotigotine patch in Parkinson’s disease with a history of intestinal operation
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    Neurological Sciences.2017; 38(1): 171.     CrossRef
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    Trends in Neurosciences.2017; 40(1): 4.     CrossRef
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    Movement Disorders.2017; 32(1): 94.     CrossRef
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    Advances in Parkinson's Disease.2017; 06(01): 1.     CrossRef
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    Journal of Movement Disorders.2017; 10(1): 29.     CrossRef
  • Gastroesophageal reflux disease with proton pump inhibitor use is associated with an increased risk of osteoporosis: a nationwide population-based analysis
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    Osteoporosis International.2016; 27(6): 2117.     CrossRef
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    Medical Sciences.2016; 4(1): 1.     CrossRef
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    C. Pellegrini, R. Colucci, L. Antonioli, E. Barocelli, V. Ballabeni, N. Bernardini, C. Blandizzi, W. J. de Jonge, M. Fornai
    Neurogastroenterology & Motility.2016; 28(12): 1781.     CrossRef
  • Gut dysfunction in Parkinson's disease
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  • Inflammation is genetically implicated in Parkinson’s disease
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    Translational Research.2015;[Epub]     CrossRef
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    Expert Opinion on Pharmacotherapy.2015; 16(16): 2449.     CrossRef
  • Gastrointestinal Dysfunctions in Parkinson’s Disease
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