Skip Navigation
Skip to contents

JMD : Journal of Movement Disorders


Author index

Page Path
HOME > Browse Articles > Author index
Ileok Jung 1 Article
Abnormal Eye Movements in Parkinsonism and Movement Disorders
Ileok Jung, Ji-Soo Kim
J Mov Disord. 2019;12(1):1-13.   Published online January 30, 2019
  • 17,649 View
  • 888 Download
  • 30 Web of Science
  • 31 Crossref
AbstractAbstract PDFSupplementary Material
Abnormal eye movements are commonly observed in movement disorders. Ocular motility examination should include bedside evaluation and laboratory recording of ocular misalignment, involuntary eye movements, including nystagmus and saccadic intrusions/oscillations, triggered nystagmus, saccades, smooth pursuit (SP), and the vestibulo-ocular reflex. Patients with Parkinson’s disease (PD) mostly show hypometric saccades, especially for the selfpaced saccades, and impaired SP. Early vertical saccadic palsy is characteristic of progressive supranuclear palsy-Richardson’s syndrome. Patients with cortico-basal syndrome typically show a delayed onset of saccades. Downbeat and gaze-evoked nystagmus and hypermetric saccades are characteristic ocular motor findings in ataxic disorders due to cerebellar dysfunction. In this review, we discuss various ocular motor findings in movement disorders, including PD and related disorders, ataxic syndromes, and hyperkinetic movement disorders. Systemic evaluation of the ocular motor functions may provide valuable information for early detection and monitoring of movement disorders, despite an overlap in the abnormal eye movements among different movement disorders.


Citations to this article as recorded by  
  • The semicircular canal function is preserved with little impact on falls in patients with mild Parkinson's disease
    Jun-Pyo Hong, Hanim Kwon, Euyhyun Park, Sun-Uk Lee, Chan-Nyoung Lee, Byung-Jo Kim, Ji-Soo Kim, Kun-Woo Park
    Parkinsonism & Related Disorders.2024; 118: 105933.     CrossRef
  • Abnormal Ocular Movement in the Early Stage of Multiple-System Atrophy With Predominant Parkinsonism Distinct From Parkinson’s Disease
    Hong Zhou, Luhua Wei, Yanyan Jiang, Xia Wang, Yunchuang Sun, Fan Li, Jing Chen, Wei Sun, Lin Zhang, Guiping Zhao, Zhaoxia Wang
    Journal of Clinical Neurology.2024; 20(1): 37.     CrossRef
  • Clinical value of video oculomotor evaluation in the differential diagnosis of multiple system atrophy and Parkinson's disease
    Dongxiao Zhou, Qian Ma, Haiwei Huang, Xue Xu
    Brain and Behavior.2024;[Epub]     CrossRef
  • Advancements in eye movement measurement technologies for assessing neurodegenerative diseases
    Tali G. Band, Rotem Z. Bar-Or, Edmund Ben-Ami
    Frontiers in Digital Health.2024;[Epub]     CrossRef
  • Smartphone video nystagmography using convolutional neural networks: ConVNG
    Maximilian U. Friedrich, Erich Schneider, Miriam Buerklein, Johannes Taeger, Johannes Hartig, Jens Volkmann, Robert Peach, Daniel Zeller
    Journal of Neurology.2023; 270(5): 2518.     CrossRef
  • Midbrain and pons MRI shape analysis and its clinical and CSF correlates in degenerative parkinsonisms: a pilot study
    C. Painous, S. Pascual-Diaz, E. Muñoz-Moreno, V. Sánchez, JC. Pariente, A. Prats-Galino, M. Soto, M. Fernández, A. Pérez-Soriano, A. Camara, E. Muñoz, F. Valldeoriola, N. Caballol, C. Pont-Sunyer, N. Martin, M. Basora, M. Tio, J. Rios, MJ. Martí, N. Barga
    European Radiology.2023; 33(7): 4540.     CrossRef
  • Saw-tooth vertical saccades in progressive supranuclear palsy
    Min-Ku Kim, Dongje Lee, Xu Yang, Hyo-Jung Kim, Jeong‑Yoon Choi, Ji-Soo Kim
    Journal of Neurology.2023; 270(7): 3644.     CrossRef
  • Non-Verbal Social Skills Assessment in Rett Syndrome: a Systematic Review
    Xin-yan Zhang, Karen Spruyt
    Review Journal of Autism and Developmental Disorders.2023;[Epub]     CrossRef
  • Spinocerebellar ataxia type 14 (SCA14) in an Argentinian family: a case report
    Niharika Duggirala, Kathie J. Ngo, Sabrina M. Pagnoni, Alberto L. Rosa, Brent L. Fogel
    Journal of Medical Case Reports.2023;[Epub]     CrossRef
  • Abnormal eye movements in Parkinson's disease: From experimental study to clinical application
    Han Li, Xue Zhang, Yong Yang, Anmu Xie
    Parkinsonism & Related Disorders.2023; 115: 105791.     CrossRef
  • Oculomotor Abnormalities in a Sheep (Ovis aries) Model of Huntington’s Disease: Towards a Biomarker for Assessing Therapeutic Efficacy
    Sebastian D. McBride, Jan Ober, Jacek Dylak, William Schneider, A. Jennifer Morton
    Journal of Huntington's Disease.2023; 12(3): 189.     CrossRef
  • Head-impulse tests aid in differentiation of multiple system atrophy from Parkinson’s disease
    Jae-Gyum Kim, Sung-Hwan Kim, Sun-Uk Lee, Chan-Nyoung Lee, Byung-Jo Kim, Ji-Soo Kim, Kun-Woo Park
    Journal of Neurology.2022; 269(6): 2972.     CrossRef
  • Overt Oculomotor Behavior Reveals Covert Temporal Predictions
    Alessandro Tavano, Sonja A. Kotz
    Frontiers in Human Neuroscience.2022;[Epub]     CrossRef
  • Eye tracking identifies biomarkers in α-synucleinopathies versus progressive supranuclear palsy
    Mahboubeh Habibi, Wolfgang H. Oertel, Brian J. White, Donald C. Brien, Brian C. Coe, Heidi C. Riek, Julia Perkins, Rachel Yep, Laurent Itti, Lars Timmermann, Christoph Best, Elisabeth Sittig, Annette Janzen, Douglas P. Munoz
    Journal of Neurology.2022; 269(9): 4920.     CrossRef
  • A Case of AOA2 With Compound Heterozygous SETX Mutations
    Hee Jin Chang, Ryul Kim, Minchae Kim, Jangsup Moon, Man Jin Kim, Han-Joon Kim
    Journal of Movement Disorders.2022; 15(2): 178.     CrossRef
  • Reading Warm-Up, Reading Skill, and Reading Prosody When Reading the My Grandfather Passage: An Exploratory Study Born Out of the Motor Planning Theory of Prosody and Reading Prosody Research
    Frank Boutsen, Eunsun Park, Justin D. Dvorak
    Journal of Speech, Language, and Hearing Research.2022; 65(6): 2047.     CrossRef
  • Eye movement abnormalities in neurodegenerative langerhans cell histiocytosis
    Lila Autier, Bertrand Gaymard, Eléonore Bayen, Antoine Del Cul, Fleur Cohen-Aubart, Nadine Martin-Duverneuil, Julien Haroche, Karima Mokhtari, Sébastien Héritier, Jean Donadieu, Khê Hoang-Xuan, Ahmed Idbaih
    Neurological Sciences.2022; 43(11): 6539.     CrossRef
  • Multiple step saccades in simply reactive saccades could serve as a complementary biomarker for the early diagnosis of Parkinson’s disease
    Wenbo Ma, Min Li, Junru Wu, Zhihao Zhang, Fangfang Jia, Mingsha Zhang, Hagai Bergman, Xuemei Li, Zhipei Ling, Xin Xu
    Frontiers in Aging Neuroscience.2022;[Epub]     CrossRef
  • The effects of age and sex on the incidence of multiple step saccades and corrective saccades
    Wenbo Ma, Mingsha Zhang
    Frontiers in Aging Neuroscience.2022;[Epub]     CrossRef
  • Oculomotor impairments in de novo Parkinson’s disease
    Meng-Xi Zhou, Qin Wang, Yin Lin, Qian Xu, Li Wu, Ya-Jing Chen, Yu-Han Jiang, Qing He, Lei Zhao, You-Rong Dong, Jian-Ren Liu, Wei Chen
    Frontiers in Aging Neuroscience.2022;[Epub]     CrossRef
  • A Story of Discovery and Change: What We Learned from Studying Nystagmus in Infancy and Childhood
    Richard W. Hertle
    Journal of Binocular Vision and Ocular Motility.2022; 72(3): 113.     CrossRef
  • Eye movement especially vertical oculomotor impairment as an aid to assess Parkinson’s disease
    JianYuan Zhang, Bin Zhang, QingGuo Ren, Qing Zhong, Ye Li, GuoTao Liu, XiaoTian Ma, CuiPing Zhao
    Neurological Sciences.2021; 42(6): 2337.     CrossRef
  • Abnormalities of smooth pursuit in Parkinson’s disease: A systematic review
    Karen Frei
    Clinical Parkinsonism & Related Disorders.2021; 4: 100085.     CrossRef
  • Central nystagmus in progressive supranuclear palsy: A neglected clinical feature?
    Maja Klarendic, Manja Hribar, Nina Bozanic Urbancic, Nina Zupancic, Milica G. Kramberger, Maja Trost, Saba Battelino, Diego Kaski, Maja Kojovic
    Parkinsonism & Related Disorders.2021; 84: 15.     CrossRef
  • Analysis of vertical eye movements in Parkinson’s disease and its potential for diagnosis
    Sajjad Farashi
    Applied Intelligence.2021; 51(11): 8260.     CrossRef
  • Abnormal eye movements in parkinsonism: a historical view
    Tereza Ko, Augusto Mädke Brenner, Nicholas Pili Monteiro, Mariana Severo Debastiani, Alberto Chitolina Nesello, Arlete Hilbig
    Arquivos de Neuro-Psiquiatria.2021; 79(5): 457.     CrossRef
  • Morphological classification and changes in dementia (Review)
    Alexandra Tudor, Antonia Vasile, Simona Trifu, Mihai Cristea
    Experimental and Therapeutic Medicine.2021;[Epub]     CrossRef
  • BCAP31-related syndrome: The first de novo report
    Berardo Rinaldi, Evelien Van Hoof, Anniek Corveleyn, Annick Van Cauter, Thomy de Ravel
    European Journal of Medical Genetics.2020; 63(2): 103732.     CrossRef
  • Hypomania and saccadic changes in Parkinson’s disease: influence of D2 and D3 dopaminergic signalling
    Esther A. Pelzer, Barbara Dillenburger, Sophie Grundmann, Vladimir Iliaev, Sophie Aschenberg, Corina Melzer, Martin Hess, Gereon R. Fink, Carsten Eggers, Marc Tittgemeyer, Lars Timmermann
    npj Parkinson's Disease.2020;[Epub]     CrossRef
  • Management of Visual Dysfunction in Patients with Parkinson’s Disease
    Joseph Savitt, Rachid Aouchiche, Bastiaan R. Bloem, Patrik Brundin
    Journal of Parkinson's Disease.2020; 10(s1): S49.     CrossRef
  • Ocular motor manifestations of movement disorders
    Grace F. Crotty, Bart K. Chwalisz
    Current Opinion in Ophthalmology.2019; 30(6): 443.     CrossRef

JMD : Journal of Movement Disorders Twitter