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Kenji Ishii 1 Article
Reorganization of the Human Somatosensory Cortex in Hand Dystonia
Maria Jose Catalan, Kenji Ishii, William Bara-Jimenez, Mark Hallett
J Mov Disord. 2012;5(1):5-8.
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AbstractAbstract PDF
Background and Purpose:

Abnormalities of finger representations in the somatosensory cortex have been identified in patients with focal hand dystonia. Measuring blood flow with positron emission tomography (PET) can be use to demonstrate functional localization of receptive fields.


A vibratory stimulus was applied to the right thumb and little finger of six healthy volunteers and six patients with focal hand dystonia to map their receptive fields using H215O PET.


The cortical finger representations in the primary somatosensory cortex were closer to each other in patients than in normal subjects. No abnormalities were found in secondary somatosensory cortex, but the somatotopy there is less well distinguished.


These data confirm prior electrophysiological and functional neuroimaging observations showing abnormalities of finger representations in somatosensory cortex of patients with focal hand dystonia.


Citations to this article as recorded by  
  • Laminar VASO fMRI in focal hand dystonia patients
    Laurentius Huber, Panagiotis Kassavetis, Omer Faruk Gulban, Mark Hallett, Silvina G. Horovitz
    Dystonia.2023;[Epub]     CrossRef
  • Sensory Alterations in Patients with Isolated Idiopathic Dystonia: An Exploratory Quantitative Sensory Testing Analysis
    Lejla Paracka, Florian Wegner, Christian Blahak, Mahmoud Abdallat, Assel Saryyeva, Dirk Dressler, Matthias Karst, Joachim K. Krauss
    Frontiers in Neurology.2017;[Epub]     CrossRef

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