- Syndrome of Inappropriate Antidiuretic Hormone Secretion Associated with Pramipexole in a Patient with Parkinson’s Disease
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Yoonjae Choi, Jeong Jin Park, Na Young Ryoo, So-Hyun Kim, Changseok Song, Im-Tae Han, Chang-Gi Hong, Choong Kun Ha, Seong Hye Choi
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J Mov Disord. 2011;4(1):46-48.
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DOI: https://doi.org/10.14802/jmd.11008
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Retraction in: J Mov Disord 2015;8(3):147
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- Syndrome of Inappropriate Antidiuretic Hormone Secretion Associated with Pramipexole in a Patient with Parkinson’s Disease
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Yoonjae Choi, Jeong Jin Park, Na Young Ryoo, So-Hyun Kim, Changseok Song, Im-Tae Han, Chang-Gi Hong, Choong Kun Ha, Seong Hye Choi
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J Mov Disord. 2010;3(2):54-56.
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DOI: https://doi.org/10.14802/jmd.10015
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29,734
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103
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 Abstract
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The syndrome of inappropriate antidiuretic hormone secretion (SIADH) can be caused by a variety of drugs. Dopaminergic drugs might enhance the secretion of the antidiuretic hormone arginine vasopressin by reducing γ-amino butyric acid release through the dopaminergic receptor in supraoptic nucleus. A 75-year-old woman with Parkinson’s disease developed asthenia, delirium, aggravated parkinsonian symptoms, and hypotonic hyponatremia along with the diagnostic criteria for SIADH during dose escalation of pramipexole. After pramipexole withdrawal, these symptoms disappeared, and sodium levels returned to normal values. The serum sodium levels of patients receiving pramipexole should be monitored, especially during dose escalation. -
Citations
Citations to this article as recorded by  - Dopaminergic Drugs and Valproate-associated Refractory Hyponatremia Over Levosulpiride-induced Parkinsonism in an Elderly Female Patient When Deprescribing was the Only Therapy
Amol Dehade, Sankha Shubhra Chakrabarti, Noti Taruni Srija Reddy, Upinder Kaur
Current Drug Safety.2025; 20(2): 232. CrossRef - Drug-induced hyponatremia in clinical care
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European Journal of Internal Medicine.2025;[Epub] CrossRef - Syndrome of Inappropriate Antidiuretic Hormone Secretion as a Presentation of Untreated Parkinson’s Disease
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