Journal of Movement Disorders

Original Article

Conceptualizing a Personalized Care Pathway for Parkinson’s Disease Using Wearable Sensors in Muslim Patients: The Ramadan Regime: Vinod Metta, Huzaifa Ibrahim, Haidar Dafsari, Rajinder K. Dhamija, Hani T. S. Benamer, Tom Loney, Mishal Abu Al-Melh, Hasna Hussain, Afsal Nalarekttil, Guy Chung-Faye, Gloria Tanjung, Bushra Alblooshi, Shaikha Almazrouei, Bassam Darwish, Mohamed Al Mheiri, Mohamed Elmahdy, Rukmini Mridula, Sai Sampath Kumar, Vinay Goyal, Karolina Popławska-Domaszewicz, Cristian Falup Pecurariu, Prashanth Kukle, Jacob Chacko, Rupam Borgohain, Kallol Ray Chaudhuri; J Mov Disord. 2026;19(1):39-48. Published online September 30, 2025; DOI: https://doi.org/10.14802/jmd.25198

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Abstract PDF: Objective
Parkinson’s disease (PD) affects approximately 2% of individuals over the age of 60. With more than two billion Muslims observing Ramadan, individuals with PD encounter specific challenges, such as deteriorating motor skills, sleep disturbances, and an increased risk of falls during fasting.
Methods
Our study focused on 75 patients with idiopathic PD divided into two groups: the Ramadan Regime group, which consisted of 50 patients whose medication was adjusted to twice daily at Suhoor and Iftar, and the Nontreatment group, which included 25 patients who abstained from medication for religious reasons. Both groups were instructed to wear a Parkinson’s KinetiGraph (PKG) wrist device.
Results
The study findings revealed that motor function worsened in the Nontreatment group (p<0.001) but improved in the Ramadan Regime group (p=0.007). Daytime sleepiness also significantly increased in the Nontreatment group (p<0.001).
Conclusion
Overall, the findings suggest that the Ramadan regime significantly enhances patient health and quality of life.

Review Articles

MRI-Guided Focused Ultrasound in Parkinson’s Disease and Essential Tremor: Incisionless but Invasive. A Narrative Review: Vinod Metta, Hani Taha Sherif Benamer, Georgios Kapsas, Rukmini Mridula, Rajesh Alugolu, Hasna Hussain, Afsal Nalarakettil, Sampath Kumar Natuva Sai, Mohamed Elmahdy, Rupam Borgohain, Kallol Ray Chaudhuri; J Mov Disord. 2025;18(4):289-303. Published online June 4, 2025; DOI: https://doi.org/10.14802/jmd.25042

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2 Web of Science
2 Crossref

Magnetic resonance-guided focused ultrasound (MRgFUS) is an emerging and promising technology for treating movement disorders, such as essential tremors and tremor-dominant Parkinson’s disease. MRgFUS utilizes advanced ultrasound transducer emitters to condense sound waves at a precisely defined point. This technology can target various brain areas, such as the pallidothalamic tract, thalamus, and pallidum, to ameliorate some of the symptoms of Parkinson’s disease and other movement disorders, such as dystonic and action-induced tremors. We review the current status of preclinical and clinical trials on the clinical use, treatment outcomes, and indications of MRgFUS.

Citations

Citations to this article as recorded by

The quality and reliability of YouTube video resources concerning patient education for Parkinson’s disease: An electronic media-based study
Xin Liu, Shuaiyan Wang, LiZhen Gan, Yuhang Wang, Longkui Jiang
Journal of International Medical Research.2026;[Epub] CrossRef
Tremor: Clinical Frameworks, Network Dysfunction and Therapeutics
Emmanuel Ortega-Robles, Oscar Arias-Carrión
Brain Sciences.2025; 15(8): 799. CrossRef

Non-Motor Fluctuations in Parkinson’s Disease: Underdiagnosed Yet Important: Iro Boura, Karolina Poplawska-Domaszewicz, Cleanthe Spanaki, Rosabel Chen, Daniele Urso, Riaan van Coller, Alexander Storch, Kallol Ray Chaudhuri; J Mov Disord. 2025;18(1):1-16. Published online December 20, 2024; DOI: https://doi.org/10.14802/jmd.24227

12,039 View
604 Download
12 Web of Science
14 Crossref

Abstract PDF

Non-motor fluctuations (NMFs) in Parkinson’s disease (PD) significantly affect patients’ well-being. Despite being identified over two decades ago, NMFs remain largely underrecognized, undertreated, and poorly understood. While they are often temporally associated with motor fluctuations (MFs) and can share common risk factors and pathophysiologic mechanisms, NMFs and MFs are currently considered distinct entities. The prevalence and severity of NMFs, often categorized into neuropsychiatric, sensory, and autonomic subtypes, vary significantly across studies due to the heterogeneous PD populations screened and the diverse evaluation tools applied. The consistent negative impact of NMFs on PD patients’ quality of life underscores the importance of further investigations via focused and controlled studies, validated assessment instruments and novel digital technologies. High-quality research is essential to illuminate the complex pathophysiology and clinical nuances of NMFs, ultimately enhancing clinicians’ diagnostic and treatment options in routine clinical practice.

Citations

Citations to this article as recorded by

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Movement Disorders Clinical Practice.2026; 13(2): 464. CrossRef
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Case Reports in Psychiatry.2026;[Epub] CrossRef
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BMC Neurology.2025;[Epub] CrossRef
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Clinical Parkinsonism & Related Disorders.2025; 12: 100330. CrossRef
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Therapeutic Advances in Neurological Disorders.2025;[Epub] CrossRef
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Tobias Warnecke, Per Odin, Rocío García-Ramos, Lydia Lopez, Delia Tulbă, Traian Flavius Dan, Dragos Catalin Jianu, Petra Bago Rožanković, Teus van Laar
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