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The Effects of Biofeedback Therapy on Anxiety and Depression in Parkinson’s Disease: A Pilot Study
Justus Chun-Yu Chen, Tzu-Yun Tseng, Jong-Ling Fuh, Yu-Hsiang Cheng, Dai-Wei Lin, Han-Lin Chiang
J Mov Disord. 2025;18(4):360-364.   Published online July 14, 2025
DOI: https://doi.org/10.14802/jmd.25097
  • 4,188 View
  • 43 Download
AbstractAbstract PDFSupplementary Material
Objective
This pilot study aimed to evaluate the feasibility and potential effects of biofeedback therapy (BT) on anxiety and depression among patients with Parkinson’s disease (PD).
Methods
A randomized waitlist-controlled trial was conducted involving 19 patients with PD and comorbid anxiety and/or depression. Anxiety and depression were assessed at baseline, posttreatment, and 1-month follow-up.
Results
All 19 patients completed the study. Compared with those of the control group, significant improvements in the Hamilton Depression Rating Scale and the anxiety subscale (but not the depression subscale) of the Hospital Anxiety and Depression Scale were observed immediately after BT. In the pooled analysis, the anxiolytic effect persisted at the 1-month follow-up, with greater improvements observed in those with more severe baseline anxiety.
Conclusion
These preliminary findings suggest that BT may help reduce anxiety symptoms among PD patients. Future studies with larger, more severely affected cohorts are needed to confirm these findings.
Case Report
Transcranial Direct Current Stimulation Combined with Action Observation and Electromyographic Biofeedback Training in a Patient with Writer’s Cramp
Yohei Okada, Chiharu Shibamoto, Yukari Osumi, Chihiro Asano, Riho Takeuchi, Sachio Nabeshima, Shu Morioka, Koji Shomoto
J Mov Disord. 2018;11(2):82-86.   Published online May 30, 2018
DOI: https://doi.org/10.14802/jmd.18007
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  • 5 Web of Science
  • 5 Crossref
AbstractAbstract PDFSupplementary Material
We present a 47-year-old right-handed woman with a 15-year history of writer’s cramp who was provided with six sessions of cathodal transcranial direct current stimulation (tDCS) combined with observation of writing actions performed by a healthy subject and electromyographic (EMG) biofeedback training to decrease EMG activities in her right forehand muscles while writing for 30 min for 4 weeks. She showed improvement in dystonic posture and writing speed after the intervention. The writing movement and writing speed scores on a writer’s cramp rating scale decreased, along with writing time. Our findings demonstrated that cathodal tDCS combined with action observation and EMG biofeedback training might improve dystonic writing movements in a patient with writer’s cramp.

Citations

Citations to this article as recorded by  
  • Effects of non-invasive brain stimulation in dystonia: a systematic review and meta-analysis
    Jordan Morrison-Ham, Gillian M. Clark, Elizabeth G. Ellis, Andris Cerins, Juho Joutsa, Peter G. Enticott, Daniel T. Corp
    Therapeutic Advances in Neurological Disorders.2022;[Epub]     CrossRef
  • New modalities and directions for dystonia care
    Genko Oyama, Nobutaka Hattori
    Journal of Neural Transmission.2021; 128(4): 559.     CrossRef
  • The Mini-BESTest is an independent predictor of falls in Parkinson Disease
    Larissa Karlla Rodrigues Lopes, Aline Alvim Scianni, Lidiane Oliveira Lima, Raquel de Carvalho Lana, Fátima Rodrigues-De-Paula
    Brazilian Journal of Physical Therapy.2020; 24(5): 433.     CrossRef
  • Modulating Observation-Execution-Related Motor Cortex Activity by Cathodal Transcranial Direct Current Stimulation
    Fengxue Qi, Michael A. Nitsche, Volker R. Zschorlich
    Brain Sciences.2019; 9(5): 121.     CrossRef
  • Beyond the target area: an integrative view of tDCS-induced motor cortex modulation in patients and athletes
    Edgard Morya, Kátia Monte-Silva, Marom Bikson, Zeinab Esmaeilpour, Claudinei Eduardo Biazoli, Andre Fonseca, Tommaso Bocci, Faranak Farzan, Raaj Chatterjee, Jeffrey M. Hausdorff, Daniel Gomes da Silva Machado, André Russowsky Brunoni, Eva Mezger, Luciane
    Journal of NeuroEngineering and Rehabilitation.2019;[Epub]     CrossRef

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