Chorea and ballism are movement disorders that result from a variety of conditions. They are an uncommon manifestation of diabetes mellitus. We report a 52-year-old diabetic man who presented with acute onset chorea-ballism with a putaminal high-signal-intensity lesion on T1-weighted magnetic resonance imaging (MRI).

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• “Diabetic striatopathy”: clinical presentations, controversy, pathogenesis, treatments, and outcomes
  Choon-Bing Chua, Cheuk-Kwan Sun, Chih-Wei Hsu, Yi-Cheng Tai, Chih-Yu Liang, I-Ting Tsai
  Scientific Reports.2020;[Epub]     CrossRef
• NEUROLOGINĖ PATOLOGIJA SERGANT 2 TIPO CUKRINIU DIABETU
  Liudmila Kimševaitė
  Medicinos teorija ir praktika.2017; 22(4): 328.     CrossRef

Hemichorea-hemiballism (HC-HB) is a complication of non-ketotic hyperglycemia (NKH); in NKH patients, the frequency of occurrence of HC-HB is greater than that of bilateral chorea. We report the case of a hyperglycemic patient who showed chorea in both the lower limbs. Magnetic resonance imaging (MRI) of the brain revealed high signal intensity on T1-weighted images of the bilateral dorsolateral putamen. The abnormal involuntary movements disappeared after oral administration of haloperidol. Our case report that chorea associated with NKH is correlated with the topography of the basal ganglia.

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• Mechanistic insights into the role of serum-glucocorticoid kinase 1 in diabetic nephropathy: A systematic review
  Saba Noor, Taj Mohammad, Gulam M. Ashraf, Joviana Farhat, Anwar L. Bilgrami, Mathew Suji Eapen, Sukhwinder Singh Sohal, Dharmendra Kumar Yadav, Md Imtaiyaz Hassan
  International Journal of Biological Macromolecules.2021; 193: 562.     CrossRef
• “Diabetic striatopathy”: clinical presentations, controversy, pathogenesis, treatments, and outcomes
  Choon-Bing Chua, Cheuk-Kwan Sun, Chih-Wei Hsu, Yi-Cheng Tai, Chih-Yu Liang, I-Ting Tsai
  Scientific Reports.2020;[Epub]     CrossRef
• T2*-based MR imaging of hyperglycemia-induced hemichorea-hemiballism
  Fang Yu, Andrew Steven, Lee Birnbaum, Wilson Altmeyer
  Journal of Neuroradiology.2017; 44(1): 24.     CrossRef
• Acute chorea in the diabetic nonketotic hyperosmolar state
  Aaron de Souza, C. Shyam Babu, Paresh K. Desai
  Basal Ganglia.2013; 3(2): 85.     CrossRef