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Diagnostic Criteria for Dementia with Lewy Bodies: Updates and Future Directions
Masahito Yamada, Junji Komatsu, Keiko Nakamura, Kenji Sakai, Miharu Samuraki-Yokohama, Kenichi Nakajima, Mitsuhiro Yoshita
J Mov Disord. 2020;13(1):1-10.   Published online November 8, 2019
DOI: https://doi.org/10.14802/jmd.19052
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AbstractAbstract PDF
The aim of this article is to describe the 2017 revised consensus criteria for the clinical diagnosis of dementia with Lewy bodies (DLB) with future directions for the diagnostic criteria. The criteria for the clinical diagnosis of probable and possible DLB were first published as the first consensus report in 1996 and were revised in the third consensus report in 2005. After discussion at the International DLB Conference in Fort Lauderdale, Florida, USA, in 2015, the International DLB Consortium published the fourth consensus report including the revised consensus criteria in 2017. The 2017 revised criteria clearly distinguish between clinical features and diagnostic biomarkers. Significant new information about previously reported aspects of DLB has been incorporated, with increased diagnostic weighting given to rapid eye movement (REM) sleep behavior disorder (RBD) and iodine-123-metaiodobenzylguanidine (MIBG) myocardial scintigraphy. Future directions include the development of the criteria for early diagnosis (prodromal DLB) and the establishment of new biomarkers that directly indicate Lewy-related pathology, including α-synuclein imaging, biopsies of peripheral tissues (skin, etc.) for the demonstration of α-synuclein deposition, and biochemical markers (cerebrospinal fluid/blood), as well as the pathological evaluation of the sensitivity and specificity of the 2017 revised diagnostic criteria. In conclusion, the revised consensus criteria for the clinical diagnosis of DLB were reported with the incorporation of new information about DLB in 2017. Future directions include the development of the criteria for early diagnosis and the establishment of biomarkers directly indicative of Lewy-related pathology.

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  • The Role of Electroconvulsive Therapy in the Treatment of Catatonia Associated With Lewy Body Dementia: A Case Report
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    Cureus.2024;[Epub]     CrossRef
  • α-Synuclein pathology from the body to the brain: so many seeds so close to the central soil
    Yunying Yang, Zhentao Zhang
    Neural Regeneration Research.2024; 19(7): 1463.     CrossRef
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    Journal of Alzheimer's Disease.2024; 97(1): 421.     CrossRef
  • Supercomplex formation of mitochondrial respiratory chain complexes in leukocytes from patients with neurodegenerative diseases
    Tsukasa Hara, Ryosuke Amagai, Ryuji Sakakibara, Ayako Okado-Matsumoto
    The Journal of Biochemistry.2024; 175(3): 289.     CrossRef
  • Latest advances in mechanisms of epileptic activity in Alzheimer’s disease and dementia with Lewy Bodies
    Mariane Vicente, Kwaku Addo-Osafo, Keith Vossel
    Frontiers in Neurology.2024;[Epub]     CrossRef
  • The clinical diagnosis of Parkinson's disease
    Renato P. Munhoz, Vitor Tumas, José Luiz Pedroso, Laura Silveira-Moriyama
    Arquivos de Neuro-Psiquiatria.2024; 82(06): 001.     CrossRef
  • Identification of Potentially Repurposable Drugs for Lewy Body Dementia Using a Network-Based Approach
    Megha Manoj, Siddarth Sowmyanarayan, Arjun V. Kowshik, Jhinuk Chatterjee
    Journal of Molecular Neuroscience.2024;[Epub]     CrossRef
  • Altered structural and functional connectivity in Posterior Cortical Atrophy and Dementia with Lewy bodies
    Neha Atulkumar Singh, Austin W. Goodrich, Jonathan Graff-Radford, Mary M. Machulda, Irene Sintini, Arenn F. Carlos, Carling G. Robinson, Robert I. Reid, Val J. Lowe, Clifford R. Jack, Ronald C. Petersen, Bradley F. Boeve, Keith A. Josephs, Kejal Kantarci,
    NeuroImage.2024; 290: 120564.     CrossRef
  • Clinicopathological correlation of cerebrospinal fluid alpha‐synuclein seed amplification assay in a behavioral neurology autopsy cohort
    Niyatee Samudra, D. Luke Fischer, Steven Lenio, Argentina Lario Lago, Peter A. Ljubenkov, Julio C. Rojas, William W. Seeley, Salvatore Spina, Adam M. Staffaroni, Jonathan Tablante, Fattin Wekselman, Jennifer Lamoureux, Luis Concha‐Marambio, Lea T. Grinber
    Alzheimer's & Dementia.2024; 20(5): 3334.     CrossRef
  • New insight of exercise on dementia; combinatory effects of physical and cognitive exercise
    Hyo-Jeong Cha, Jun Hong Park, Changwan Hong
    Molecular & Cellular Toxicology.2024; 20(4): 767.     CrossRef
  • Diagnostic Challenge of an Advanced Stage Dementia Case
    Emin Taşkıran
    European Journal of Geriatrics and Gerontology.2024; 6(1): 73.     CrossRef
  • Dementia with Lewy bodies
    Cheri M. Jrolf
    JAAPA.2024;[Epub]     CrossRef
  • Absolute quantitation of sympathetic nerve activity using [123I] metaiodobenzylguanidine SPECT-CT in neurology
    Shintaro Saito, Kenichi Nakajima, Junji Komatsu, Takayuki Shibutani, Hiroshi Wakabayashi, Hiroshi Mori, Aki Takata, Kenjiro Ono, Seigo Kinuya
    EJNMMI Reports.2024;[Epub]     CrossRef
  • Sympathetic 123I-metaiodobenzylguanidine index for Lewy body disease: probability-based diagnosis and identifying patients exempt from late imaging
    Kenichi Nakajima, Takeshi Matsumura, Junji Komatsu, Hiroshi Wakabayashi, Kenjiro Ono, Seigo Kinuya
    Annals of Nuclear Medicine.2024; 38(10): 814.     CrossRef
  • The usefulness of combined analysis using CIScore and VSRAD parameters for differentiating between dementia with Lewy body and Alzheimer’s disease
    Gaku Honda, Shigeki Nagamachi, Mai Takahashi, Yukie Higuma, Tomonobu Tani, Kosuke Hida, Kengo Yoshimitsu, Koji Ogomori, Yoshio Tsuboi
    Japanese Journal of Radiology.2024; 42(10): 1206.     CrossRef
  • Biofluid Detection of Pathological α-Synuclein in the Prodromal Phase of Synucleinopathies
    Annika Kluge, Alex Iranzo, Daniela Berg, Bastiaan R. Bloem, Lorraine V. Kalia, Ron B. Postuma
    Journal of Parkinson's Disease.2024; 14(s2): S323.     CrossRef
  • Multiple system atrophy: Diagnostic challenges and a proposed diagnostic algorithm
    Deepmala Nandanwar, Daniel D. Truong
    Clinical Parkinsonism & Related Disorders.2024; 11: 100271.     CrossRef
  • Substantia nigra hyperechogenicity and brain ventricular size as biomarkers of early dementia with Lewy bodies
    Anna Planas-Ballvé, Jose Rios, Mireia Gea, Neus Rabaneda-Lombarte, Lourdes Ispierto, Laia Grau, Marta Jiménez, Cynthia Cáceres, Sílvia Martínez, Katrin Beyer, Ramiro Álvarez, Pau Pastor, Dolores Vilas
    Alzheimer's Research & Therapy.2024;[Epub]     CrossRef
  • The Diagnostic Challenges of Late-onset Neuropsychiatric Symptoms and Early-onset Dementia: A Clinical and Neuropathological Case Study
    Miguel Restrepo-Martinez, Ramiro Ruiz-Garcia, Jacob Houpt, Lee Cyn Ang, Sumit Chaudhari, Elizabeth Finger
    Cognitive and Behavioral Neurology.2024;[Epub]     CrossRef
  • Quantitative proteomic analysis using a mouse model of Lewy body dementia induced by α-synuclein preformed fibrils injection
    Fatih Akkentli, In kyu Jang, Yoonseop Choi, Young Min, Jinhee Park, Heejin Jo, Leoni Kim, Aashi Mendpara, Bikram Bains, Dongyoon Yoo, Jinchong Xu, Chan Hyun Na, Sung-Ung Kang
    Frontiers in Dementia.2024;[Epub]     CrossRef
  • Magnetic resonance imaging in the diagnosis of progressive supranuclear palsy: A case report and review of literature
    Baraka Alphonce, Francisca Komanya, Mbelwa Bitesigilwe, John R. Meda, Azan Nyundo
    Clinical Case Reports.2023;[Epub]     CrossRef
  • Parkinson's disease fluid biomarkers for differential diagnosis of atypical parkinsonian syndromes
    Jun Yang, Ayotimofe Idowu, Liana Rosenthal, Xiaobo Mao
    Clinical and Translational Discovery.2023;[Epub]     CrossRef
  • Neurofilament light chain is increased in the parahippocampal cortex and associates with pathological hallmarks in Parkinson’s disease dementia
    Irene Frigerio, Max A. Laansma, Chen-Pei Lin, Emma J. M. Hermans, Maud M. A. Bouwman, John G. J. M. Bol, Yvon Galis-de Graaf, Dagmar H. Hepp, Annemieke J. M. Rozemuller, Frederik Barkhof, Wilma D. J. van de Berg, Laura E. Jonkman
    Translational Neurodegeneration.2023;[Epub]     CrossRef
  • Machine learning-based prediction of conversion coefficients for I-123 metaiodobenzylguanidine heart-to-mediastinum ratio
    Koichi Okuda, Kenichi Nakajima, Chiemi Kitamura, Michael Ljungberg, Tetsuo Hosoya, Yumiko Kirihara, Mitsumasa Hashimoto
    Journal of Nuclear Cardiology.2023; 30(4): 1630.     CrossRef
  • Costs During the Last Five Years of Life for Patients with Clinical and Pathological Confirmed Diagnosis of Lewy Body Dementia and Alzheimer’s Disease
    Carolyn W. Zhu, Yian Gu, Anton J. Kociolek, Kayri K. Fernandez, Stephanie Cosentino, Yaakov Stern
    Journal of Alzheimer's Disease.2023; 92(2): 457.     CrossRef
  • Early- and late-onset of isolated rapid eye movement sleep behavior disorder: A retrospective cohort study
    Li Zhou, Bei Huang, Jing Wang, Steven WH. Chau, Joey WY. Chan, Jihui Zhang, Mandy WM. Yu, Jessie CC. Tsang, Shirley Xin Li, Vincent CT. Mok, Yun Kwok Wing, Yaping Liu
    Sleep Medicine.2023;[Epub]     CrossRef
  • Parkinson Disease Dementia Management: an Update of Current Evidence and Future Directions
    Oliver Phillips, Debolina Ghosh, Hubert H. Fernandez
    Current Treatment Options in Neurology.2023; 25(5): 93.     CrossRef
  • Rapidly progressive dementia with severe insomnia: an unusual case of progressive supranuclear palsy mimicking dementia with Lewy bodies
    Rae On Kim, Eun Ji Lee, Seong-Ik Kim, Sung-Hye Park, Kyum-Yil Kwon
    Neurological Sciences.2023; 44(8): 2953.     CrossRef
  • Significance of clinical symptoms and red flags in early differential diagnosis of Parkinson’s disease and atypical Parkinsonian syndromes
    Nils Schröter, Thilo van Eimeren, Joseph Classen, Johannes Levin, Christoph Redecker, Martin Wolz, Lars Tönges
    Journal of Neural Transmission.2023; 130(6): 839.     CrossRef
  • Electroencephalography in young onset dementia
    Casey W Brown, Huei-Yang Chen, Peter K Panegyres
    BMC Neurology.2023;[Epub]     CrossRef
  • Clinical trials in dementia with Lewy bodies: the evolving concept of co-pathologies, patient selection and biomarkers
    Lucy L. Gibson, Carla Abdelnour, Joyce Chong, Clive Ballard, Dag Aarsland
    Current Opinion in Neurology.2023;[Epub]     CrossRef
  • Coexistence of Posterior Cortical Atrophy and Parkinson’s Disease
    Eun-Byul Ko, Il-Joong Hwang, Jung-Woo Kim, Dar-Eun Jung, Ju-Suk Lee, Sang-Won Yoo, Joong-Seok Kim
    Journal of the Korean Neurological Association.2023; 41(3): 216.     CrossRef
  • Toward a new nosology of neurodegenerative diseases
    Manuel Menéndez‐González
    Alzheimer's & Dementia.2023; 19(8): 3731.     CrossRef
  • Autonomic dysfunction in dementia with Lewy bodies: Focusing on cardiovascular and respiratory dysfunction
    Katsuyoshi Mizukami
    Psychiatry and Clinical Neurosciences Reports.2023;[Epub]     CrossRef
  • Beyond Strains: Molecular Diversity in Alpha-Synuclein at the Center of Disease Heterogeneity
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    International Journal of Molecular Sciences.2023; 24(17): 13199.     CrossRef
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    Medicinal Chemistry.2023; 19(10): 946.     CrossRef
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    Yael Hirschberg, Natalia Valle‐Tamayo, Oriol Dols‐Icardo, Sebastiaan Engelborghs, Bart Buelens, Roosmarijn E. Vandenbroucke, Yannick Vermeiren, Kurt Boonen, Inge Mertens
    Journal of Extracellular Vesicles.2023;[Epub]     CrossRef
  • The connection between cerebral amyloid angiopathy and Alzheimer’s disease
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    European Radiology.2023; 34(4): 2171.     CrossRef
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  • Autonomic symptoms are predictive of dementia with Lewy bodies
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  • A Systematic Review and Comparison of Neurocognitive Features of Late-Life Attention-Deficit/Hyperactivity Disorder and Dementia With Lewy Bodies
    Jennifer L. Prentice, Morgan J. Schaeffer, Alexandra K. Wall, Brandy L. Callahan
    Journal of Geriatric Psychiatry and Neurology.2021; 34(5): 466.     CrossRef
  • Dementia with Lewy bodies in first-generation immigrants in a European memory clinic
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  • The development of new method to differentiate between Dementia with Lewy bodies and Alzheimer’s disease by cerebral perfusion SPECT-comparison to CIScore
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    Nature Medicine.2021; 27(3): 411.     CrossRef
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    Cells.2021; 10(3): 656.     CrossRef
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  • A direct comparison of the 2005 and 2017 criteria for dementia with Lewy bodies
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    Psychogeriatrics.2020; 20(5): 785.     CrossRef
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    Koichi Okuda, Kenichi Nakajima, Chiemi Kitamura, Yumiko Kirihara, Mitsumasa Hashimoto, Seigo Kinuya
    Scientific Reports.2020;[Epub]     CrossRef

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